Pharmaceutical Chemicals 1,4-Butanediol /jenny@ycphar.com

Ad Description

Product Name: 1,4-Butanediol
Alias:1,4-Dihydroxybutane;1,4-Butylene glycol;Tetramethylene glycol
CAS NO.: 110-63-4
EINECS NO.: 203-786-5
MF: C4H10O2
APPEARANCE: colorless viscous liquid
Flash Point: 135°C
Solubility: Miscible
Density: 1.017g/mL

1,4-Butanediol (1,4-B, butylene glycol, or BD) is a thick, colourless liquid which is nearly odorless with a distinct bitter taste. 1,4-Butanediol is used industrially as a solvent and in the manufacture of some types of plastics, elastic fibers and polyurethanes. In organic chemistry, 1,4-butanediol is used for the synthesis of ?-butyrolactone (GBL).

In humans, it acts as a depressant and a prodrug for GHB where 1ml is equivalent to 1g of GHB. It is used as a recreational intoxicant with effects similar to alcohol.
1,4-Butanediol, as well as GBL, will dissolve most types of plastic over time.For this reason, it is recommended to only transport and store the drug using a glass container, standard gelatin capsules (not vegetarian), or high-density polyethylene plastic (also known as #2 recycled plastic). To check the type of plastic used on a bottle, one can look at the bottom for a number in the triangle shaped recycling label.

Physical effects

Stimulation and Sedation - At lower doses, 1,4-butanediol is physically stimulating, encouraging movement and wakefulness. At higher doses, however, it becomes physically sedating, encouraging sleep and lethargy.
Motor control loss
Respiratory depression - Many reportedly experience an abnormal pattern of breathing characterized by progressively deeper and sometimes faster breathing followed by a gradual decrease that results in a temporary stop in breathing called an apnea.

Cognitive effects

Empathy, love and sociability enhancement - Unlike alcohol which merely increases sociability through disinhibition, 1,4-butanediol presents strong entactogenic effects which, although weaker than that of MDMA, are still prominent and well-defined.
Information processing suppression
Thought deceleration
Anxiety suppression
Increased libido - - This effect is manifested differently in comparison to dopaminergic stimulants such as cocaine or amphetamine in a way that is more emotionally driven and cerebral in its perception as opposed to being primarily physically driven by dopaminergic stimulation. It is most felt when dosage remains low to moderate and intensifies proportionally to the duration of consumption

Toxicity and harm potential

1,4-Butanediol is not active in its own right; its mechanism of action stems from its identity as a prodrug of GHB, meaning that it is rapidly converted into GHB in the body.
GHB is considered to be a safe and non-toxic substance when used responsibly or medically. The LD50 is above the active dosage, and there is no danger of acute toxicity when this compound is taken at appropriate dosages. However, it can be dangerous when used as a recreational drug or abused. There have been many negative reports from recreational users who have overdosed, combined GHB with alcohol or other drugs, or accidentally dosed themselves unexpectedly.

One publication has investigated 226 deaths attributed to GHB.Seventy-one deaths (34%) were caused by GHB alone while the other deaths were from respiratory depression caused by interaction with alcohol or other drugs.To avoid a possible overdose of GHB/1,4-Butanediol, it is important to start with a low dose and work your way up slowly by increasing the dosage in small increments as the exact toxic dosage is unknown.

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Classified Id :208346
Posted On : 11 Feb 2018
Category : Home Store
Sub Category : Others

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